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InChiKey: BOZRFEQDOFSZBV-DHIUTWEWSA-N
ERRβ2 facilitates the block in G2/M
In xenograft models of acute myeloid leukemia and multiple myeloma
Morimoto M
could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11
EL-102 islignan InChiKey: BOZRFEQDOFSZBV-DHIUTWEWSA-NEL102 is a inhibitor of HIF1 , Which can inhibit tubulin polymerisation and decreased microtubule stability. target: HIF1IC 5020 40 nM. in vitro : EL102 is a cytotoxic agent and also displays cytostatic properties, through flow cytometric analysis of PI stained cells cultured for 24, 48 and 72 h, following treatment. EL102 induces apoptosis and causes G2 M arrest, preventing the cell from entering into mitosis. In vivo: CWR22 tumours were taken from
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