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C-176 (750/375 nmol C-176 per mouse in 200 μL corn oil) significantly reduces the CMA-mediated induction of serum levels of type I IFNs and IL-6
blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM)
InChi: InChI=1S/C21H16N2O4/c24-19-10-17(20(25)15-7-2-1-6-14(15)19)23-18(21(26)27)9-12-11-22-16-8-4-3-5-13(12)16/h1-8
CAS Number: 2242636-28-6
92%) and increases the proportion of cells in G0-G1 phase and to a lesser extent in G2/M
7-Chlorokynurenic acid Size:Contact [email protected] for quotation C-176 (750/375 nmol C-176 per7 Chlorokynurenic acid (7 CKA) is a potent and selective antagonist of the glycine B coagonist site of the N methyl D aspartate (NMDA) receptor (IC50=0. 56 M). 7 Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0. 59 M. 7 Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery. Product information CAS Number: 18000 24 3 Molecular Weight: 223. 61 Formula:
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