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Smiles: CNS(=O)(=O)C[C@@H]1CC[C@H](CC1)N(C)C1N=CN=C2NC=CC2=1
2013 May 30
79(2):286-97
Castoreno AB
CF53 binds to both the BD1 and BD2 domains of BRD2
G140 atrole Smiles: CNS(=O)(=O)C[C@@H]1CC[C@H](CC1)N(C)C1N=CN=C2NC=CC2=1G140 is a potent and selective inhibitor of cyclic GMP AMP synthase (cGAS), with IC50s of 14. 0 nM and 442 nM for h cGAS and m cGAS, respectively. G140 has anti inflammatory activity. Product information CAS Number: 2369751 07 3 Molecular Weight: 379. 24 Formula: C17H16Cl2N4O2 Chemical Name: 1 [6,7 dichloro 9 (1 methyl 1H pyrazol 3 yl) 1H,2H,3H,4H,5H pyrido[4,3 b]indol 2 yl] 2 hydroxyethan 1 one Smiles:
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