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CHR-2797 exerts antiproliferative effects against a range of tumor cell lines
3-Dihydrobenzo[b][1
potently suppressing signaling and proliferation in cancer cells
CAS Number: 60-56-0
Gefitinib - CAS# 184475-35-2 Size:Solid 2 mg CCCN(CCC)CCC1=CC=CC2NC(=O)CC1=2Gefitinib, also known as ZD1839, is an anilinoquinazoline with antineoplastic activity. Gefitinib inhibits the catalytic activity of numerous tyrosine kinases including the epidermal growth factor receptor (EGFR), which may result in inhibition of tyrosine kinase dependent tumor growth. Specifically, this agent competes with the binding of ATP to the tyrosine kinase domain of EGFR, thereby inhibiting receptor autophosphorylation and resulting in