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Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth
TPX-0131 (2-10 mg/kg
N-((4-chlorophenyl)methyl)-N'
It attenuates the levels of nuclear p65-NFκB
Formula: C17H17F3N2O2
Methylamino-PEG5-azide 7-264) Targeting RNA polymerase I withMethylamino PEG5 azide is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2055046 24 5 Molecular Weight: 320. 39 Formula: C13H28N4O5 Chemical Name: 19 azido 5,8,11,14,17 pentaoxa 2 azanonadecane Smiles: CNCCOCCOCCOCCOCCOCCN=[N+]=[N ] InChiKey: DHHWWGQHCQSYRP UHFFFAOYSA N InChi: InChI=1S C13H28N4O5 c1 15 2 4 18 6 8 20 10 12 22 13 11 21 9 7 19 5 3 16 17 14 h15H,2 13H2,1H3 Technical Data Appearance:
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