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TAS-103 dihydrochloride Size:Solid 2 mg 686770-61-6

SKU: 19038448044

4.5
USD100.00 USD146.00

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Description

686770-61-6

Entecavir results in an impressive reduction of serum viral DNA with covalently closed circular DNA and hepatitis B viral core antigen negativity in liver biopsy specimens

KU-57788 reduces pDNA-PKcs (S2056) protein expression in liver cancer cells

InChi: InChI=1S/C17H20N4O5

InChi: InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8

TAS-103 dihydrochloride Size:Solid 2 mg 686770-61-6TAS 103, also known as BMS 247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS 103 has been reported to be a potent topoisomerase II poison. TAS 103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0. 05). The combination with CDDP augmented the antitumor activity of TAS 103 (p<0. 05), indicating that CDDP is one of the most potent candidates

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